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OR07-2 Elucidating The Mechanisms Of Action Of Mkrn3 In A Novel Mouse Model Of Delayed Puberty.
Makorin Ring Finger Protein 3 (MKRN3) is an important neuroendocrine player in the control of pubertal timing. Loss-of-function mutations in MKRN3 are the most common genetic cause of central precocious puberty. Mice have high levels of hypothalamic Mkrn3 expression in the juvenile period, which rap...
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| Publicado en: | J Endocr Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Endocrine Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6554928/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR07-2 |
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