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Makorin RING finger protein 3 and central precocious puberty
Makorin RING finger protein 3 (MKRN3) is a key inhibitor of the hypothalamic–pituitary–gonadal axis. Loss-of-function mutations in MKRN3 cause familial and sporadic central precocious puberty (CPP), while polymorphisms are associated with age at menarche. To date, 115 patients with CPP carrying MKRN...
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| Publicado no: | Curr Opin Endocr Metab Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7518508/ https://ncbi.nlm.nih.gov/pubmed/32984644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coemr.2020.08.003 |
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