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Makorin RING finger protein 3 and central precocious puberty

Makorin RING finger protein 3 (MKRN3) is a key inhibitor of the hypothalamic–pituitary–gonadal axis. Loss-of-function mutations in MKRN3 cause familial and sporadic central precocious puberty (CPP), while polymorphisms are associated with age at menarche. To date, 115 patients with CPP carrying MKRN...

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Foilsithe in:Curr Opin Endocr Metab Res
Main Authors: Maione, Luigi, Naulé, Lydie, Kaiser, Ursula B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518508/
https://ncbi.nlm.nih.gov/pubmed/32984644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coemr.2020.08.003
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