OR29-3 Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare malignancy with frequently dismal prognosis and few therapies. Patients with locoregional ACC routinely receive surgery and adjuvant mitotane, but >50% recur with metastases even after complete resection. Histological grade (Ki67>10% or >20 mitoses/5...

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Dades bibliogràfiques
Publicat a:J Endocr Soc
Autors principals: Mohan, Dipika, Lerario, Antonio, Else, Tobias, Almeida, Madson, Vinco, Michelle, Rege, Juilee, Mariani, Beatriz, Zerbini, Maria, Mendonca, Berenice, Latronico, Ana Claudia, Marie, Suely, Rainey, William, Giordano, Thomas, Fragoso, Maria, Hammer, Gary
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Adrenal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554777/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR29-3
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