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Adapting dCas9-APEX2 for subnuclear proteomic profiling

Genome organization and subnuclear protein localization are essential for normal cellular function and have been implicated in the control of gene expression, DNA replication, and genomic stability. The coupling of chromatin conformation capture (3C), chromatin immunoprecipitation and sequencing, an...

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Bibliografische gegevens
Gepubliceerd in:Methods Enzymol
Hoofdauteurs: Gao, Xin D., Rodríguez, Tomás C., Sontheimer, Erik J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554722/
https://ncbi.nlm.nih.gov/pubmed/30691651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.10.030
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