In Situ Capture of Chromatin Interactions by Biotinylated dCas9

Cis-regulatory elements (CREs) are commonly recognized by correlative chromatin features, yet the molecular composition of the vast majority of CREs in chromatin remains unknown. Here we describe a CRISPR affinity purification in situ of regulatory elements (CAPTURE) approach to unbiasedly identify...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Liu, Xin, Zhang, Yuannyu, Chen, Yong, Li, Mushan, Zhou, Feng, Li, Kailong, Cao, Hui, Ni, Min, Liu, Yuxuan, Gu, Zhimin, Dickerson, Kathryn E., Xie, Shiqi, Hon, Gary C., Xuan, Zhenyu, Zhang, Michael Q., Shao, Zhen, Xu, Jian
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857456/
https://ncbi.nlm.nih.gov/pubmed/28841410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.003
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