Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease that causes pain and bone deterioration driven by an increase in prostaglandins (PGs) and inflammatory cytokines. Current treatments focus on inhibiting prostaglandin production, a pro-inflammatory lipid metabolite, with NSAID drugs; however, other...

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Pubblicato in:Front Pharmacol
Autori principali: McReynolds, Cindy B., Hwang, Sung Hee, Yang, Jun, Wan, Debin, Wagner, Karen, Morisseau, Christophe, Li, Dongyang, Schmidt, William K., Hammock, Bruce D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554663/
https://ncbi.nlm.nih.gov/pubmed/31214021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00533
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