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Omecamtiv Mecarbil Slows Myosin Kinetics in Skinned Rat Myocardium at Physiological Temperature

Heart failure is a life-threatening condition that occurs when the heart muscle becomes weakened and cannot adequately circulate blood and nutrients around the body. Omecamtiv mecarbil (OM) is a compound that has been developed to treat systolic heart failure via targeting the cardiac myosin heavy c...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Kieu, Thinh T., Awinda, Peter O., Tanner, Bertrand C.W.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554472/
https://ncbi.nlm.nih.gov/pubmed/31103235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.020
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