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Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter

Long-chain fatty acids activate the free fatty acid receptor 1 (FFA1) and FFA4. In the gastrointestinal system, FFA1 and FFA4 have been found in the pancreas and intestine. Fatty food and decreased lower esophageal sphincter (LES) motility are associated with gastroesophageal reflux disease. The eff...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Tsai, Ching-Chung, Li, Yi-Chen, Chang, Li-Ching, Tey, Shu-Leei, Lin, Kai-Jen, Huang, Shih-Che
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554435/
https://ncbi.nlm.nih.gov/pubmed/31214048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00676
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