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Divergent Allele Advantage Provides a Quantitative Model for Maintaining Alleles with a Wide Range of Intrinsic Merits

The Major Histocompatibility Complex (MHC) is the most genetically diverse region of the genome in most vertebrates. Some form of balancing selection is necessary to account for the extreme diversity, but the precise mechanism of balancing selection is unknown. Due to the way MHC molecules determine...

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Vydáno v:Genetics
Hlavní autoři: Stefan, Thorsten, Matthews, Louise, Prada, Joaquin M., Mair, Colette, Reeve, Richard, Stear, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553829/
https://ncbi.nlm.nih.gov/pubmed/30952668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302022
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