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Selection maintains signaling function of a highly diverged intrinsically disordered region

Intrinsically disordered regions (IDRs) are characterized by their lack of stable secondary or tertiary structure and comprise a large part of the eukaryotic proteome. Although these regions play a variety of signaling and regulatory roles, they appear to be rapidly evolving at the primary sequence...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zarin, Taraneh, Tsai, Caressa N., Nguyen Ba, Alex N., Moses, Alan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338452/
https://ncbi.nlm.nih.gov/pubmed/28167781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614787114
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