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Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions

Intrinsically disordered protein regions are abundant in eukaryotic proteins and lack stable tertiary structures and enzymatic functions. Previous studies of disordered region evolution based on interspecific alignments have revealed an increased propensity for indels and rapid rates of amino acid s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Genome Biol Evol
मुख्य लेखकों: Khan, Tahsin, Douglas, Gavin M., Patel, Priyenbhai, Nguyen Ba, Alex N., Moses, Alan M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494057/
https://ncbi.nlm.nih.gov/pubmed/26047845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv105
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