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Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection
The highly polymorphic genes of the major histocompatibility complex (MHC) play a key role in adaptive immunity. Divergent allele advantage, a mechanism of balancing selection, is proposed to contribute to their exceptional polymorphism. It assumes that MHC genotypes with more divergent alleles allo...
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| Veröffentlicht in: | Mol Biol Evol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6106954/ https://ncbi.nlm.nih.gov/pubmed/29893875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msy116 |
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