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Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Most clinically used opioids are thought to induce analgesia through activation of the mu opioid receptor (MOR). However, disparities have been observed between the efficacy of opioids in activating the MOR in vitro and in inducing analgesia in vivo. In addition, some clinically used opioids do not...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Olson, Keith M., Duron, David I., Womer, Daniel, Fell, Ryan, Streicher, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553708/
https://ncbi.nlm.nih.gov/pubmed/31170174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217371
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