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Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Most clinically used opioids are thought to induce analgesia through activation of the mu opioid receptor (MOR). However, disparities have been observed between the efficacy of opioids in activating the MOR in vitro and in inducing analgesia in vivo. In addition, some clinically used opioids do not...

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Vydáno v:PLoS One
Hlavní autoři: Olson, Keith M., Duron, David I., Womer, Daniel, Fell, Ryan, Streicher, John M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553708/
https://ncbi.nlm.nih.gov/pubmed/31170174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217371
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