CRL4(Mahj) E3 ubiquitin ligase promotes neural stem cell reactivation

The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown. Here, we show that CRL4(Mahj), an evolutionarily c...

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Vydáno v:PLoS Biol
Hlavní autoři: Ly, Phuong Thao, Tan, Ye Sing, Koe, Chwee Tat, Zhang, Yingjie, Xie, Gengqiang, Endow, Sharyn, Deng, Wu-Min, Yu, Fengwei, Wang, Hongyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553684/
https://ncbi.nlm.nih.gov/pubmed/31170139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000276
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