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Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease
The cullin 4-RING ubiquitin ligase (CRL4) family employs multiple DDB1–CUL4 associated factors substrate receptors to direct the degradation of proteins involved in a wide spectrum of cellular functions. Aberrant expression of the cullin 4A (CUL4A) gene is found in many tumor types, while mutations...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Frontiers Research Foundation
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355902/ https://ncbi.nlm.nih.gov/pubmed/22649780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00021 |
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