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SUN-LB055 Targeting Mutant p53 Alone or in Combination with a Phosphatidylserine Specific Antibody Suppresses Growth and Metastasis of Human Breast Cancer: A Strategy Towards Enhancing Personalized Medicine
Mutations in the tumor suppressor p53 gene are frequently associated with various cancers, including human breast cancer. Unlike wild-type p53 (wtp53), mutant p53 protein (mtp53) fails to promote apoptosis, resulting in tumor cell survival and resistance to chemotherapeutic drugs. Consequently, rest...
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| Publicado no: | J Endocr Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6553059/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-LB055 |
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