APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice

BACKGROUND: Approximately 15–20% of all human breast cancers are classified as triple-negative because they lack estrogen and progesterone receptors and Her-2-neu, which are commonly targeted by chemotherapeutic drugs. New treatment strategies are therefore urgently needed to combat triple-negative...

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Veröffentlicht in:Breast Cancer (Dove Med Press)
Hauptverfasser: Liang, Yayun, Besch-Williford, Cynthia, Cook, Matthew T, Belenchia, Anthony, Brekken, Rolf A, Hyder, Salman M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681124/
https://ncbi.nlm.nih.gov/pubmed/31534364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S208706
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