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Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors

Breast cancer progression depends upon the elaboration of a vasculature sufficient for the nourishment of the developing tumor. Breast tumor cells frequently contain a mutant form of p53 (mtp53), a protein which promotes their survival. The aim of this study was to determine whether combination ther...

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Detalhes bibliográficos
Main Authors: Liang, Yayun, Besch-Williford, Cynthia, Benakanakere, Indira, Thorpe, Philip E., Hyder, Salman M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916972/
https://ncbi.nlm.nih.gov/pubmed/20349129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0851-x
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