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Synthetic progestins differentially promote or prevent DMBA-induced mammary tumors in Sprague-Dawley rats

Recent clinical trials demonstrate that combined oral dosing with estrogen and progestin increases the incidence of breast cancer in post-menopausal women. Similarly, in a rat model system of mammary carcinogenesis, the synthetic progestin medroxyprogesterone acetate (MPA) decreases latency and incr...

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Autori principali: Benakanakere, Indira, Besch-Williford, Cynthia, Carroll, Candace E., Hyder, Salman M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980323/
https://ncbi.nlm.nih.gov/pubmed/20699413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0064
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