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SUN-532 Interferon Gamma-1b Does Not Increase Markers of Bone Resorption in Autosomal Dominant Osteopetrosis

In autosomal dominant osteopetrosis type 2 (ADO2) CLCN7 mutations cause impaired osteoclast function. Severe consequences include skeletal fragility despite high bone mass, osteomyelitis, osteonecrosis, bone marrow failure, and severe cranial nerve impingement. There is no effective medical treatmen...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Imel, Erik, Liu, Ziyue, Acton, Dena, Coffman, Melissa, Gebregziabher, Netsanet, Tong, Yan, Econs, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552866/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-532
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