SUN-532 Interferon Gamma-1b Does Not Increase Markers of Bone Resorption in Autosomal Dominant Osteopetrosis

In autosomal dominant osteopetrosis type 2 (ADO2) CLCN7 mutations cause impaired osteoclast function. Severe consequences include skeletal fragility despite high bone mass, osteomyelitis, osteonecrosis, bone marrow failure, and severe cranial nerve impingement. There is no effective medical treatmen...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Imel, Erik, Liu, Ziyue, Acton, Dena, Coffman, Melissa, Gebregziabher, Netsanet, Tong, Yan, Econs, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Bone and Mineral Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552866/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-532
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