Oral Iron Replacement Normalizes Fibroblast Growth Factor 23 in Iron Deficient Patients with Autosomal Dominant Hypophosphatemic Rickets

Autosomal dominant hypophosphatemic rickets (ADHR) is caused by mutations impairing cleavage of fibroblast growth factor 23 (FGF23). FGF23 gene expression increases during iron deficiency. In humans and mice with the ADHR mutation, iron deficiency results in increased intact FGF23 concentrations and...

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Publicado en:J Bone Miner Res
Main Authors: Imel, Erik A., Liu, Ziyue, Coffman, Melissa, Acton, Dena, Mehta, Rakesh, Econs, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333537/
https://ncbi.nlm.nih.gov/pubmed/31652009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3878
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