SUN-LB042 The Novel Androgen 11β-Methyl-19-Nortestosterone Dodecylcarbonate (11β-MNTDC) Effectively Suppresses Gonadotropins and Testosterone in Healthy Men: A Potential Oral Male Hormonal Contraceptive

Background: 11β-MNTDC is an orally bioavailable prodrug of 11β-methyl-19-nortestosterone (11β-MNT). It is a modified testosterone (T) with androgenic and progestational activity being developed as a male contraceptive. 11β-MNTDC suppressed serum T and gonadotropin production while maintaining androg...

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Publicat a:J Endocr Soc
Autors principals: Yuen, Fiona, Thirumalai, Arthi, Pham, Cindy, Swerdloff, Ronald, Anawalt, Bradley, Liu, Peter, Amory, John, Bremner, William, Dart, Clint, Blithe, Diana, Long, Jill, Page, Stephanie, Wang, Christina
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Reproductive Endocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552783/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-LB042
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