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Phosphorylation of HSP90 by protein kinase A is essential for the nuclear translocation of androgen receptor
The androgen receptor (AR) is often activated in prostate cancer patients undergoing androgen-ablative therapy because of the activation of cellular pathways that stimulate the AR despite low androgen levels. In many of these tumors, the cAMP-dependent protein kinase A (PKA) pathway is activated. Pr...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552429/ https://ncbi.nlm.nih.gov/pubmed/30992362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007420 |
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