Phosphorylation of HSP90 by protein kinase A is essential for the nuclear translocation of androgen receptor

The androgen receptor (AR) is often activated in prostate cancer patients undergoing androgen-ablative therapy because of the activation of cellular pathways that stimulate the AR despite low androgen levels. In many of these tumors, the cAMP-dependent protein kinase A (PKA) pathway is activated. Pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Dagar, Manisha, Singh, Julie Pratibha, Dagar, Gunjan, Tyagi, Rakesh K., Bagchi, Gargi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Editors' Picks
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552429/
https://ncbi.nlm.nih.gov/pubmed/30992362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007420
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