Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells

The androgen receptor (AR) is activated in patients with castration resistant prostate cancer (CRPC) despite low circulating levels of androgen, suggesting that intracellular signaling pathways and non-androgenic factors may contribute to AR activation. Many G-protein coupled receptors (GPCR) and th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Singh, Julie Pratibha, Dagar, Manisha, Dagar, Gunjan, Kumar, Sudhir, Rawal, Sudhir, Sharma, Ravi Datta, Tyagi, Rakesh Kumar, Bagchi, Gargi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470385/
https://ncbi.nlm.nih.gov/pubmed/32881870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226056
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