SAT-150 Forkhead Box Protein O1 (foxo1) Regulates Hepatic Serine Protease Inhibitor B1 (serpinb1) Expression In A Cell Non-autonomous Fashion

Forkhead box O (FoxO) proteins are major targets of insulin action, and FoxO1 mediates insulin’s effects on hepatic glucose metabolism. We previously reported that serine protease inhibitor B1 (serpinB1) is a liver-secreted factor (hepatokine) that promotes adaptive β-cell proliferation in response...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: El Ouaamari, Abdelfattah, O-Sullivan, InSug, Shirakawas, Jun, Basile, Giorgio, Wenwei, Zhang, Sandra, Rogers, Thomou, Thomas, Liew, Chong Wee, Kulkarni, Rohit, Unterman, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Diabetes Mellitus and Glucose Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552238/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-150
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