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Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion

FoxO proteins are major targets of insulin action, and FoxO1 mediates the effects of insulin on hepatic glucose metabolism. We reported previously that serpinB1 is a liver-secreted factor (hepatokine) that promotes adaptive β-cell proliferation in response to insulin resistance in the liver-specific...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: El Ouaamari, Abdelfattah, O-Sullivan, InSug, Shirakawa, Jun, Basile, Giorgio, Zhang, Wenwei, Roger, Sandra, Thomou, Thomas, Xu, Shanshan, Qiang, Guifen, Liew, Chong Wee, Kulkarni, Rohit N., Unterman, Terry G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341384/
https://ncbi.nlm.nih.gov/pubmed/30459233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006031
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