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SAT-421 Cell-Specific Ablation of GnRH Neurons Using Kisspeptin-Saporin in the Preoptic Area of Sheep, but Not Mice

Sheep have been a useful preclinical model for the exploration of the role of kisspeptin and its receptor, KISS1R, in the control of pulsatile section of gonadotropin releasing hormone (GnRH). However, lack of reagents to interrogate KISS1R neurons in sheep has limited progress in this species. To a...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Porter, Danielle, Moore, Aleisha, Goodman, Robert, Hileman, Stanley, Coolen, Lique, Lehman, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551997/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-421
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