Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes

Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in the arcuate nucleus play a key role in GnRH pulse generation, with kisspeptin driving GnRH release and neurokinin B (NKB) and dynorphin acting as start and stop signals, respectively. In this study, we tes...

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Bibliographic Details
Main Authors: Goodman, Robert L., Hileman, Stanley M., Nestor, Casey C, Porter, Katrina L., Connors, John M., Hardy, Steve L., Millar, Robert P., Cernea, Maria, Coolen, Lique M., Lehman, Michael N.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2013
Subjects:
Neuroendocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800763/
https://ncbi.nlm.nih.gov/pubmed/23959940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1331
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