Evidence That Dynorphin Acts Upon KNDy and GnRH Neurons During GnRH Pulse Termination in the Ewe

A subpopulation of neurons located within the arcuate nucleus, colocalizing kisspeptin, neurokinin B, and dynorphin (Dyn; termed KNDy neurons), represents key mediators of pulsatile GnRH secretion. The KNDy model of GnRH pulse generation proposes that Dyn terminates each pulse. However, it is unknow...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Weems, Peyton W, Coolen, Lique M, Hileman, Stanley M, Hardy, Steven, McCosh, Rick B, Goodman, Robert L, Lehman, Michael N
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693042/
https://ncbi.nlm.nih.gov/pubmed/30016419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00435
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