SAT-566 Cofilin Is a Mediator of RET-Promoted Medullary Thyroid Carcinoma Cell Migration, Invasion and Proliferation

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor that originates from parafollicular thyroid C cells, accounting for 5% -10% of thyroid cancers. In all inherited cases of MTC, and in about 40% of sporadic cases, activating mutations of the receptor tyrosine kinase proto-oncogene RET...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Peverelli, Erika, GIARDINO, ELENA, CATALANO, ROSA, BARBIERI, ANNAMARIA, Treppiedi, Donatella, MANGILI, FEDERICA, Spada, Anna, Arosio, Maura, Mantovani, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Thyroid
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551961/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-566
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