Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior

Although generally benign, pituitary tumors frequently show local invasiveness and resistance to pharmacological therapy. After the demonstration of the existence of pituitary gland stem cells, over the past decade, the presence of a stem cell subpopulation in pituitary tumors has been investigated,...

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Detalhes bibliográficos
Main Authors: Giovanna Mantovani, Elena Giardino, Donatella Treppiedi, Rosa Catalano, Federica Mangili, Anna Spada, Maura Arosio, Erika Peverelli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Endocrinology
Assuntos:
pituitary tumors
stem cells
tumourigenesis
resistance
invasiveness
recurrence
Acesso em linha:https://www.frontiersin.org/article/10.3389/fendo.2019.00745/full
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