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An integrated quantitative structure and mechanism of action-activity relationship model of human serum albumin binding

BACKGROUND: Traditional quantitative structure-activity relationship models usually neglect the molecular alterations happening in the exposed systems (the mechanism of action, MOA), that mediate between structural properties of compounds and phenotypic effects of an exposure. RESULTS: Here, we prop...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Serra, Angela, Önlü, Serli, Coretto, Pietro, Greco, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551915/
https://ncbi.nlm.nih.gov/pubmed/31172382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-019-0359-2
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