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An integrated quantitative structure and mechanism of action-activity relationship model of human serum albumin binding

BACKGROUND: Traditional quantitative structure-activity relationship models usually neglect the molecular alterations happening in the exposed systems (the mechanism of action, MOA), that mediate between structural properties of compounds and phenotypic effects of an exposure. RESULTS: Here, we prop...

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Pubblicato in:J Cheminform
Autori principali: Serra, Angela, Önlü, Serli, Coretto, Pietro, Greco, Dario
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551915/
https://ncbi.nlm.nih.gov/pubmed/31172382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-019-0359-2
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