p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice

Muscle wasting is the key manifestation of cancer-associated cachexia, a lethal metabolic disorder seen in over 50% of cancer patients. Autophagy is activated in cachectic muscle of cancer hosts along with the ubiquitin-proteasome pathway (UPP), contributing to accelerated protein degradation and mu...

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Vydáno v:Cell Stress
Hlavní autoři: Liu, Zhelong, Sin, Ka Wai Thomas, Ding, Hui, Doan, HoangAnh Amy, Gao, Song, Miao, Hongyu, Wei, Yahui, Wang, Yiman, Zhang, Guohua, Li, Yi-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Shared Science Publishers OG 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551802/
https://ncbi.nlm.nih.gov/pubmed/31225455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.11.163
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