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p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice
Muscle wasting is the key manifestation of cancer-associated cachexia, a lethal metabolic disorder seen in over 50% of cancer patients. Autophagy is activated in cachectic muscle of cancer hosts along with the ubiquitin-proteasome pathway (UPP), contributing to accelerated protein degradation and mu...
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| Publié dans: | Cell Stress |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Shared Science Publishers OG
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6551802/ https://ncbi.nlm.nih.gov/pubmed/31225455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.11.163 |
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