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Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase
BACKGROUND: Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to muscle atrophy because of increased muscle protein degradation. However, the intracellular signalling mechanism that mediates ActRIIB‐activated muscle catabolism is poorly defined. METHODS: We investigated the...
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| Izdano u: | J Cachexia Sarcopenia Muscle |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377410/ https://ncbi.nlm.nih.gov/pubmed/27897407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12145 |
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