Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase

BACKGROUND: Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to muscle atrophy because of increased muscle protein degradation. However, the intracellular signalling mechanism that mediates ActRIIB‐activated muscle catabolism is poorly defined. METHODS: We investigated the...

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Publicat a:J Cachexia Sarcopenia Muscle
Autors principals: Ding, Hui, Zhang, Guohua, Sin, Ka Wai Thomas, Liu, Zhelong, Lin, Ren‐Kuo, Li, Min, Li, Yi‐Ping
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377410/
https://ncbi.nlm.nih.gov/pubmed/27897407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12145
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