Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase

BACKGROUND: Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to muscle atrophy because of increased muscle protein degradation. However, the intracellular signalling mechanism that mediates ActRIIB‐activated muscle catabolism is poorly defined. METHODS: We investigated the...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Ding, Hui, Zhang, Guohua, Sin, Ka Wai Thomas, Liu, Zhelong, Lin, Ren‐Kuo, Li, Min, Li, Yi‐Ping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377410/
https://ncbi.nlm.nih.gov/pubmed/27897407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12145
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