Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells

BACKGROUND: Antagonists of the V1a vasopressin receptor (V1aR) are emerging as a strategy for slowing progression of CKD. Physiologically, V1aR signaling has been linked with acid-base homeostasis, but more detailed information is needed about renal V1aR distribution and function. METHODS: We used a...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Giesecke, Torsten, Himmerkus, Nina, Leipziger, Jens, Bleich, Markus, Koshimizu, Taka-aki, Fähling, Michael, Smorodchenko, Alina, Shpak, Julia, Knappe, Carolin, Isermann, Julian, Ayasse, Niklas, Kawahara, Katsumasa, Schmoranzer, Jan, Gimber, Niclas, Paliege, Alexander, Bachmann, Sebastian, Mutig, Kerim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551786/
https://ncbi.nlm.nih.gov/pubmed/31097611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018080816
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