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Synthesis and cytotoxicity of a biotinylated CC-1065 analogue

BACKGROUND: The use of pretargeting technology for cancer imaging and treatment has made significant progress in the last few years. This approach takes advantage of the fact that biotin binds strongly to proteins avidin and streptavidin. Thus, a non-toxic tumor cell specific antibody is conjugated...

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Bibliografiske detaljer
Main Authors: Wang, Yuqiang, Yuan, Huiling, Wright, Susan C, Wang, Hong, Larrick, James W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC65513/
https://ncbi.nlm.nih.gov/pubmed/11846891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-2-1
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