Synthesis and cytotoxicity of a biotinylated CC-1065 analogue

BACKGROUND: The use of pretargeting technology for cancer imaging and treatment has made significant progress in the last few years. This approach takes advantage of the fact that biotin binds strongly to proteins avidin and streptavidin. Thus, a non-toxic tumor cell specific antibody is conjugated...

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izdano v:	BMC Chem Biol
Principais autores:	Wang, Yuqiang, Yuan, Huiling, Wright, Susan C, Wang, Hong, Larrick, James W
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2002
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC65513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11846891/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6769-2-1
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