Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease

Positive transcription elongation factor b (P-TEFb) functions as a central regulator of transcription elongation. Activation of P-TEFb occurs through its dissociation from the transcriptionally inactive P-TEFb/HEXIM1/7SK snRNP complex. However, the mechanisms of signal-regulated P-TEFb activation an...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Sun, Yongzhan, Liu, Zhiheng, Cao, Xinyi, Lu, Yi, Mi, Zeyun, He, Chaoran, Liu, Jing, Zheng, Zhanye, Li, Mulin Jun, Li, Tiegang, Xu, Dechao, Wu, Ming, Cao, Ying, Li, Yuhao, Yang, Baoxue, Mei, Changlin, Zhang, Lirong, Chen, Yupeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551191/
https://ncbi.nlm.nih.gov/pubmed/31183407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw3593
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