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Direct Quantification of Gamma H2AX by Cell-Based High Throughput Screening for Evaluation of Genotoxicity of Pesticides in a Human Thyroid Cell Line

Genotoxicity is thought to be the cause of many cancers. Genotoxicity due to environmental toxins may be partly responsible for the dramatic increase in the incidence of papillary thyroid cancer over the past two decades. Here, we present a fully automatable assay platform that directly quantifies t...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Hershman, Jerome M., France, Bryan, Hon, Kevin, Damoiseaux, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550478/
https://ncbi.nlm.nih.gov/pubmed/28640454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22103
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