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High throughput evaluation of gamma-H2AX

The DNA double-strand break (DSB) is the primary lethal lesion after therapeutic radiation. Thus, the development of assays to detect and to quantitate these lesions could have broad preclinical and clinical impact. Phosphorylation of histone H2AX to form γ-H2AX is a known marker for irradiation-ind...

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Detalhes bibliográficos
Main Authors: Avondoglio, Dane, Scott, Tamalee, Kil, Whoon Jong, Sproull, Mary, Tofilon, Philip J, Camphausen, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740844/
https://ncbi.nlm.nih.gov/pubmed/19703306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-31
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