Unexpected Role of Matrix Gla Protein in Osteoclasts: Inhibiting Osteoclast Differentiation and Bone Resorption

Matrix Gla protein (MGP) is an extracellular protein responsible for inhibiting mineralization. MGP inhibits osteoblast mineralization and bone formation by regulating the deposition of bone matrix. However, Mgp(–/–) mice display an osteopenic phenotype. To explain this contradiction, we investigate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Zhang, Yan, Zhao, Liting, Wang, Naining, Li, Jing, He, Fang, Li, Xu, Wu, Shufang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549463/
https://ncbi.nlm.nih.gov/pubmed/30988158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00012-19
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker