Unexpected Role of Matrix Gla Protein in Osteoclasts: Inhibiting Osteoclast Differentiation and Bone Resorption

Matrix Gla protein (MGP) is an extracellular protein responsible for inhibiting mineralization. MGP inhibits osteoblast mineralization and bone formation by regulating the deposition of bone matrix. However, Mgp(–/–) mice display an osteopenic phenotype. To explain this contradiction, we investigate...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Zhang, Yan, Zhao, Liting, Wang, Naining, Li, Jing, He, Fang, Li, Xu, Wu, Shufang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549463/
https://ncbi.nlm.nih.gov/pubmed/30988158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00012-19
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