Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma

Medulloblastoma is a highly malignant pediatric brain tumor associated with poor outcome. Developing treatments that target the cancer stem cell (CSC) population in medulloblastoma are important to prevent tumor relapse and induce long-lasting clinical responses. We utilized medulloblastoma neurosph...

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Eckerdt, Frank, Bell, Jonathan B., Beauchamp, Elspeth M., Clymer, Jessica, Blyth, Gavin T., Kosciuczuk, Ewa M., Ma, Quanhong, Chen, David Z., Horbinski, Craig, Goldman, Stewart, Munshi, Hidayatullah G., Hashizume, Rintaro, Platanias, Leonidas C.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548590/
https://ncbi.nlm.nih.gov/pubmed/30842251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1193
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