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CD28 homolog is a strong activator of natural killer cells for lysis of B7H7(+) tumor cells

The CD28–B7 family of receptor–ligand pairs regulates lymphocyte responses through costimulation and coinhibition. It includes checkpoint inhibitors, such as PD-1, which limit antitumor and antivirus T-cell responses. CD28 homolog (CD28H) and B7H7 have been identified as a receptor–ligand pair in th...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Zhuang, Xiaoxuan, Long, Eric O
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548580/
https://ncbi.nlm.nih.gov/pubmed/31018957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0733
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