Human CD16 as a lysis receptor mediating direct natural killer cell cytotoxicity

In addition to their role in peptide antigen presentation, class I MHC proteins also play a critical role in inhibiting natural killer (NK) cytotoxicity through interaction with NK inhibitory receptors. Thus, NK cells are cytotoxic to virus-infected and tumor cells that have lost class I MHC protein...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mandelboim, Ofer, Malik, Pratap, Davis, Daniel M., Jo, Chang H., Boyson, Jonathan E., Strominger, Jack L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10318937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.10.5640
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