Natural killer cell lines kill autologous β(2)-microglobulin-deficient melanoma cells: Implications for cancer immunotherapy

Cancer vaccines used to generate specific cytotoxic T lymphocytes are not effective against tumor cells that have lost or suppressed expression of their class I major histocompatibility complex proteins. This loss is common in some cancers and particularly in metastatic lesions. We show that β(2)-mi...

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Bibliografiske detaljer
Main Authors: Porgador, Angel, Mandelboim, Ofer, Restifo, Nicholas P., Strominger, Jack L.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24276/
https://ncbi.nlm.nih.gov/pubmed/9371813
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