Natural killer cell lines kill autologous β(2)-microglobulin-deficient melanoma cells: Implications for cancer immunotherapy

Cancer vaccines used to generate specific cytotoxic T lymphocytes are not effective against tumor cells that have lost or suppressed expression of their class I major histocompatibility complex proteins. This loss is common in some cancers and particularly in metastatic lesions. We show that β(2)-mi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Porgador, Angel, Mandelboim, Ofer, Restifo, Nicholas P., Strominger, Jack L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371813/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.24.13140
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